Grados Académicos:
 

  • Bioquímico, Universidad de Concepción, Chile (1996)
  • Doctor en Ciencias Biológicas, Universidad de Concepción, Chile (2003)

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    Distinciones obtenidas:
     

  • Premio Hermann Niemeyer F., otorgado por la Sociedad de Bioquímica y Biología Molecular de Chile en su XXIV Reunión Anual (24-27 de septiembre de 2001, Termas de Chillán, Chile).

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  • Beca "Pew Latin American Fellows Program" (septiembre 2003 a septiembre 2005), para realización de estadía postdoctoral en The Stowers Institute, Kansas City, MO, USA.

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    Publicaciones:
     

  • Gutiérrez, J., Paredes, R., Cruzat, F., Hill, D., van Wijnen, A., Lian, J., Stein, G., Stein, J., Imbalzano, A., and Montecino, M. (2007) Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter. Journal of Biological Chemistry, 282 (13): 9445-9457.

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  • Gutiérrez, J., Chandy, M., Carrozza, M., and Workman, J. (2007) Activation domains drive nucleosome eviction by SWI/SNF. The EMBO Journal, 26 (3): 730-740.

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  • Chandy, M., Gutiérrez, J., Prochasson, P., and Workman, J. (2006) SWI/SNF displaces SAGA acetylated nucleosomes. Eukaryotic Cell, 5 (10): 1738-1747.

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  • Li, B., Pattenden, S., Lee, D., Gutiérrez, J., Chen, J., Seidel, C., Gerton, J., and Workman, J. (2005) Preferential occupancy of histone variant H2AZ at inactive promoters influences local histone modifications and chromatin remodeling. Proceedings of the National Academy of Sciences, 102 (51): 18385-18390.

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  • Jin, J., Cai, Y., Yao, T., Gottschalk, A., Florens, L.,Swanson, S., Gutiérrez, J., Coleman, M., Workman, J., Mushegian, A., Washburn, M., Conaway, R., and Conaway, J. (2005) A mammalian chromatin remodeling complex with similarities to the yeast INO80 complex. Journal of Biological Chemistry, 280 (50): 41207-41212.

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  • Pattenden, S., Chandy, M., Gutiérrez, J., and Workman, J. (2005) Chromatin dynamics rule the genome. Genome Biology, 6 (11): 355.

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  • Paredes, R., Gutiérrez, J., Gutierrez, S., Allison, L., Puchi, M., Imschenetzky, M., van Wijnen, A., Lian, J., Stein, G., Stein, J., and Montecino, M. (2002) Interaction of the 1a, 25-dihydroxy vitamin D3 receptor, Runx/Cbfa, and YY1 transcription factors at the distal promoter region of the bone-specific osteocalcin gene requires nucleosomal remodeling. Biochemical Journal, 363: 667-676.

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  • Villagra, A., Gutiérrez, J., Paredes, R., Sierra, J., Puchi, M., Imschenetzky, M., van Wijnen, A., Lian, J., Stein, G., Stein, J., and Montecino, M. (2002) Reduced CpG methylation is associated with transcriptional activation of the bone-specific rat osteocalcin gene in osteoblasts. Journal of Cellular Biochemistry, 85: 112-122.

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  • Medina, R., Gutiérrez, J., Puchi, M., Imschenetzky, M., and Montecino, M. (2001) Cytoplasm of sea urchin unfertilized eggs contains a nucleosome remodeling activity. Journal of Cellular Biochemistry, 83:554-562.

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  • Gutiérrez, J., Sierra, J., Medina, R., Puchi, M., Imschenetzky, M., van Wijnen, A., Lian, J., Stein, G., Stein, J., and Montecino, M. (2000) Interaction of CBFa/AML/PEBP2a transcription factors with nucleosomes containing promoter sequences requires flexibility in the translational positioning of the histone octamer and exposure of the CBFa site. Biochemistry, 39 (44): 13565-13574.

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    Email: lgutier@udec.cl

    Última actualización: 21/05/2007